PROVEN
SAFE &
EFFECTIVE
Due to its close promximity to the prostate,
the rectum is most at risk for radiation exposure.
If you or your loved one has been diagnosed with prostate cancer and is planning to undergo radiation therapy, you may want to consider a Barrigel rectal spacer to help minimize potential short and long-term bowel complications.1
BOWEL COMPLICATIONS MAY INCLUDE
BOWEL
COMPLICATIONS
MAY INCLUDE
SHORT-TERM
Needing to have a bowel movement more often than usual (bowel incontinence)
Diarrhea
Loose stools
Hemorrhoids
LONG-TERM
Inflammation of the rectum
(radiation proctitis)
Rectal bleeding
Narrowing of the rectum
Hemorrhoids
Chronic diarrhea
Development of an ulcer in the rectum
SHORT-TERM
Needing to have a bowel movement more often than usual (bowel incontinence)
Diarrhea
Loose stools
Hemorrhoids
LONG-TERM
Inflammation of the rectum
(radiation proctitis)
Rectal bleeding
Narrowing of the rectum
Hemorrhoids
Chronic diarrhea
Development of an ulcer in the rectum
spacers is
98.5% of Barrigel patients had a significant reduction in radiation to the rectum.1
WHAT IS THE BENEFIT OF REDUCED
RADIATION TO THE RECTUM?
WHAT IS THE
BENEFIT OF
REDUCED
RADIATION TO
THE RECTUM
Barrigel reduced the rate of complications, including1
Inflammation of the rectum (Radiation Proctitis)
Diarrhea
Hemorrhoids
To date there have been zero Barrigel-related complications2,3
In his own WORDS
“I felt comfortable in having the Barrigel procedure, as its success rate shows very little chance of rectum damage which was a high concern of mine when considering radiation treatment for prostate cancer.”
A LEGACY OF LONG-TERM SAFETY
A LEGACY OF
LONG-TERM
SAFETY
Barrigel is made from Non-Animal Stabilized Hyaluronic Acid (NASHA®). Hyaluronic acid is a substance naturally present in the human body and is highly compatible and fully absorbable. NASHA has a proven history of safety and efficacy in a wide variety of medical applications, including pediatric medicine.4
References
1. Mariados NF, Orio PF III, Schiffman Z et al. Hyaluronic acid spacer for hypofractionated prostate radiation therapy: A randomized clinical trial. JAMA Oncol. 2023;e1-e8.
2. Data on file. Palette Life Sciences.
3. MAUDE - Manufacturer and User Facility Device Experience. Accessed: September 08, 2023. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfmaude/search.cfm.
4. Q-Med. NASHA- the Monograph. Uppsala, Sweden.
5. Restylane® celebrates 25 years of natural-looking results with its signature line of hyaluronic acid fillers. 2021. Available at: https://www.prnewswire.com/news-releases/restylane-celebrates-25-years-of-natural-looking-results-with-its-signature-line-of-hyaluronic-acid-fillers-301388779.html. Accessed Sept 30, 2021.
